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Verruciform xanthoma

Verruciform xanthoma is an uncommon lesion with a predilection for the oral mucosa of middle-aged persons or on the scrotum of middle‒aged-to-elderly Japanese men. The most common site for.. Verruciform xanthoma is an uncommon benign lesion that has a verruciform (wart -like) appearance, but it may appear polypoid, papillomatous, or sessile. The verruciform was first described by Shafer in 1971 on the oral mucosa

A 50-year-old man presented with a several month history of a polypoid papule on the scrotum. A dense accumulation of macrophages with foamy cytoplasm was exhibited in the biopsy specimen leading to a diagnosis of verruciform xanthoma BACKGROUND: Verruciform xanthoma (VX) is a benign lesion that primarily affects the oral cavity, most frequently the gingiva. VX lesions are characterized by xanthoma cells (lipid-laden macrophages or foam cells) found in the superficial connective tissue

Twenty-one cases of verruciform xanthoma are reported, bringing to fifty the total cases in the literature. The lesion was found most often in middle-aged persons, and the most common location was the gingiva or alveolar ridge. The cause of the verruciform xanthoma is still uncertain Verruciform xanthoma (VX) of the oral cavity is an uncommon, reactive lesion of unknown etiology. In this study, we present a large series of VX with analysis of demographics, clinical appearance, histologic presentation and extensive review of literature. To the best of our knowledge, this is the l Verruciform xanthoma is an uncommon benign lesion of undetermined etiology. It is a superficial normolipemic xanthoma, probably reflecting a multifactorial reactive and dystrophic process unrelated to HPV. It is noteworthy that in a small and superficial biopsy, xanthoma cells may be scanty and can be missed, especially if the pathologist is. 38 year old man with multiple, coexisting verruciform xanthomas of anogenital region associated with cutaneous trauma (J Cutan Pathol 2010;37:895) 50 year old man with scrotal verruciform xanthoma (Dermatol Online J 2014;20:21253) 64 year old man with penile verruciform xanthoma (Arch Ital Urol Androl 2016;88:284

Verruciform Xanthoma: Background, Pathophysiology, Etiolog

  1. The biological profile of oral verruciform xanthoma (VX) is presented based on a world-wide literature survey of 282 cases. From 1979 onwards, extraoral cases have also been reported
  2. Verruciform xanthoma. Verruciform xanthoma is a rare entity not associated with dyslipidaemias. It most commonly affects the mouth, where it is found as a solitary, asymptomatic lesion on the gingiva and is associated with chronic graft-versus-host disease. On the genitalia, it has been called a Vegas (verruciform genital-associated) xanthoma and presents as a yellow-brown or red verrucous plaque
  3. antly affecting the oral cavity, but also skin and female anogenital mucosa. It can be flat, papular-warty or crateriform-cystic. Furthermore it can simulate HPV viral lesion such as condyloma and malignant neoplasia such as verrucous squam
  4. We report three cases of verruciform xanthoma (VX) in male patients aged 82, 88 and 39 years, respectively. The clinical appearance was of a mulberry-like area consisting of small papillae, which is typical of and specific to VX, and the diagnosis were histologically confirmed in all cases
  5. Verruciform xanthoma (VX) is rare with no racial or gender predilection. It may be seen in conjunction with the CHILD syndrome, discoid lupus, epidermal nevi, lichen planus or chronic lymphedema. What is the Cause of the Disease
  6. Verruciform xanthoma is a relatively uncommon lesion. Half of the reported cases occurred in the gingiva or alveolar ridge. In most cases, the clinical impressions are papilloma or verrucous carcinoma, which demonstrates the importance of the clinical and pathological recognition of this lesion

Verruciform xanthoma can be misdiagnosed as verrucous carcinoma both clinically and microscopically if a superficial biopsy is performed. Verrucous carcinoma is of particular importance because, although it is a carcinoma, it shows little or no epidermal cytologic atypia Verruciform xanthoma is a benign mucocutaneous, uncommon, nonsymptomatic lesion of uncertain etiopathology, which occurs mostly on the oral mucosa of middle-aged individuals. Histopathologically, VX is diagnosed by presence of lipid-laden foam cells in papillary region of connective tissue Background . Verruciform xanthoma is an uncommon benign tumor, which exhibits a wide range of clinical patterns. The occurrence of the lesion in patients with immune-mediated mucocutaneous diseases may suggest a role of localized epithelial cell damage and chronic inflammation in its pathogenesis. Case Report . A case of verruciform xanthoma on the tongue of a 56-year-old female with oral.

Verruciform xanthoma - Wikipedi

  1. Verruciform xanthoma Brad W. Neville, D.D.S.,* and Dwight R. Weathers, D.D.S., M.S.D.,** Atlanta Ga. EMORY UNIVERSITY SCHOOL OF DENTISTRY Twenty-one cases of verruciform xanthoma are reported, bringing to fifty the total cases in the literature. The lesion was found most often in middle-aged persons, and the most common location was the gingiva.
  2. Verruciform xanthoma • Uncommon benine oral mocusal lesion that occasionally may be found on the skin typically on the genitalia 17. Etiology and Pathogenesis The cause is Unknown (NSDHL) 18. Clinical feature: whites granular and papillary (2 mm to 2 cm) 19..
  3. Oral Verruciform Xanthoma: A case report . By Dr P Dhanrajani (p1954sa@yahoo.com.au) BDS, MDS, MSc, MSC, FRACDS, FDSRCS, FFDRCSI. Oral Surgeon . Dental News September 2018 . A 49 years old male patient presented to the oral surgery clinic with a history of a plaque like lesion on the right ventral aspect of the tongue
  4. Verruciform xanthoma (VX) is a xanthoma variant that commonly presents as a single verrucous, papillomatous, or keratotic plaque or nodule on the oral or anogenital mucosa. Other less common locations are the perioral area and the esophagus and other parts of the aerodigestive tract
  5. antly in the oral cavity which occasionally affects skin and genitals. It appears as a papule or single.

Verruciform xanthoma - PubMe

Verruciform xanthoma: immunohistochemical characterization

verruciform xanthoma: A benign solitary lesion of the oral cavity-occasionally extraoral, described as a red, asymptomatic lesion occurring at age 40 Treatment Complete excisio Verrucous xanthoma is a benign histiocytic lesion of macrophage derivation. We describe a woman with a non-mucosal verruciform xanthoma located on her right thumb and review the features of patients with verruciform acral-associated xanthoma. A 69-year-old woman presented with a lesion on her right thumb of eight years duration that had been previously treated with liquid nitrogen cryotherapy. Verruciform Xanthoma. Home Genitourinary External Genitalia Verruciform Xanthoma. Verruciform Xanthoma. Verruciform Xanthoma. Verruciform Xanthoma. Verruciform Xanthoma. Verruciform Xanthoma. Verruciform Xanthoma. Follow us Verruciform xanthoma is a distinct clinicopathologic entity first reported in oral mucosa1 and subsequently on female genital skin.2 It is most frequently located in the oral mucosa but has been reported in other mucocutaneous locations (glottis, epiglottis, larynx, lips, nose, neck, axilla, extremities, digits, penis, scrotum, and anal region) as well Verruciform xanthoma is a rare, granular, plaque-like lesion which occurs on mucosal surfaces and is characterized by acanthosis with xanthoma cells in the dermis between rete pegs. A case of verruciform xanthoma is reported which occurred on the sacral region in a patient with recessive dystrophic epidermolysis bullosa (RDEB)

Verruciform xanthoma William G. Shafer, D.D.S., M.S., Indianapolis, Ind. DEPARTMENT OF ORAL PATHOLOGY, INDIANA UNIVERSITY SCHOOL OF DENTISTRY A previously undescribed lesion of the oral mucosa is discussed, and certain, clinical and histologie features of fifteen cases are described. The term verrucifwm, xwvthoma has been widely applied to this. Verruciform xanthoma: Report of two cases Vera Teixeira, José P Reis, Óscar Tellechea, Ricardo Vieira, Américo Figueiredo Dermatology Online Journal 18 (5): 10 Department of Dermatology, Coimbra University Hospital, Portugal Abstract. Verruciform xanthoma (VX) is an uncommon benign condition of unknown etiology, which frequently affects the oral mucosa in adults

Verruciform xanthoma is a benign, wart-like lesion that can clinically mimic squamous cell carcinoma. We describe two teenage patients with severe genodermatoses, recessive dystrophic epidermolysis bullosa (RDEB), and keratitis-ichthyosis-deafness (KID) syndrome, respectively, each found to have plaques suspicious for malignancy, later demonstrated on histopathologic examination to be.

Oral verruciform xanthoma represents an uncommon entity, which affects mainly oral mucosa. This paper presents the major clinical and histological features of oral verruciform xanthoma and reports a case on the tongue. The differential diagnosis and a literature review are also provided in light of recent information Verruciform xanthoma (VX) is a rare finding thought to be caused by epidermal damage from trauma or inflammation and has been reported in a limited number of patients with recessive dystrophic epidermolysis bullosa (RDEB). Herein, we describe a 20‐year‐old woman with RDEB who developed a large, verrucous, pink plaque on the posterior thigh. Verruciform xanthoma within carcinoma in situ. J Oral Maxillofac Surg, 1989. 47:398-400 12. Fite C, Plantier F, Dupin N: Vulvar verruciform xanthoma ten cases associated with lichen sclerosus, lichen planus, or other conditions. Arch Dermatol

Verruciform xanthoma

Verruciform xanthoma is a benign proliferation most commonly occurring in the oral cavity. Extraoral lesions are rare and usually arise on the vulva, penis, scrotum, and extremities. 88 Most patients present with a solitary lesion, although coexistence of multiple lesions can occur Oral Verruciform Xanthoma: A Case Report and Literature Review Kourosh Nakhaei IntroductionVerruciform xanthoma (VX) is an uncommon benign mucocutaneous lesion that resembles virus-induced papilloma but has an unknown etiology and uncertain nature Verruciform xanthoma is a rare lesion first described by Shafer 1 in 1971. It usually appears as a solitary lesion most commonly presenting on the oral mucosa. In 2003, a worldwide survey of the literature profiled a total of 282 oral and 46 extraoral VX lesions. 2 Extraoral cutaneous lesions are less common and usually present in the. Verruciform Xanthoma-Histopathologically: A Distinct Entit

Verruciform xanthoma is a benign, soft tissue lesion occurring on the orogenital mucosa. Presentation of oral lesions can be pink, yellow, or gray raised plaque or papule with granular, papillary. Twenty-one cases of verruciform xanthoma are reported, bringing to fifty the total cases in the literature. The lesion was found most often in middle-aged persons, and the most common location was the gingiva or alveolar ridge Oral verruciform xanthoma (OVX) is an uncommon benign lesion, which affects predominantly oral mucosa, usually presents a normal or reddish colour and sometimes pale or hyperkeratotic pattern, and has a rough, pebbly surface, with either sessile or pedunculated base, and diameter between 2 mm and 1.5 cm. The frequency of this lesion. Verruciform xanthoma (VX) is a rare, benign lesion that presents in the oral cavity, skin, or genital organs as a verrucous, papillomatous, or flat papule with varying colors. VX has indistinct. Verruciform xanthoma in the setting of cutaneous trauma and chronic inflammation: report of a patient and a brief review of the literature. Cumberland L , Dana A , Resh B , Fitzpatrick J , Goldenberg

Oral Verruciform Xanthoma: A Series of 212 Cases and

Verruciform xanthoma is an uncommon benign lesion that has a verruciform (wart-like) appearance, but it may appear polypoid, papillomatous, or sessile.: 535 The verruciform was first described by Shafer in 1971 on the oral mucosa Verruciform xanthoma is an uncommon mucocutaneous condition of uncertain cause that only occasionally affects the skin. The histopathology is distinctive for the presence of foamy histiocytes present within elongated dermal papillae. Although simpl Verruciform xanthoma is a wart-like benign lesion. The classic histologic appearance consists of foamy histiocytes within elongated dermal papillae and epithelial acanthosis. The lesion most commonly occurs in the oral cavity, but has been reported in extra-oral sites such as the penis, scrotum, and vulva. The clinical and histologic characteristics of verruciform genital-associated (Vegas.

Oral verruciform xanthoma (OVX) is an uncommon benign lesion that is characterized histologically by the accumulation of several foamy macrophages in the lamina propria papillae. The pathogenesis of OVX has not been completely elucidated, although the significance of macrophage polarization (M1, tumor suppression; and M2, tumor promotion) and the contribution of M2 macrophages to angiogenesis. Verruciform xanthoma [VX] is an uncommon benign mucocutaneous lesion of unknown etiology. This rare, harmless lesion usually presents as sessile or pedunculated, pale yellowish-to-red, papillary. Verruciform xanthoma (VX) has been described occurring both extraorally and more frequently on the oral mucosa (usually on the hard palate or gingivae) . The occurrence of multiple or disseminated. Verruciform xanthoma (VX) is a benign epithelial lesion that was described and termed by Shafer in 1971 [], although was known from the 1960s [].Clinically, most oral lesions are slow-growing, asymptomatic, solitary plaque or nodules (only on rare occasions are they multiple) with papillary, verrucous surfaces or flat-topped nodules colored pink, red, yellow, or white [3, 4]

Flat-type verruciform xanthoma of the tongue and its

Pathology Outlines - Cutaneous verruciform xanthom

  1. xanthoma, and skin verruciform xanthomas have also reported as concomitant symptoms of many epithelial proliferative diseases. Therefore, some researchers insist that verruciform xanthoma is a secondary disease [13]. In addition to histological features, verruciform xanthoma can also be identified using immunohistochemical characteristics
  2. Verruciform xanthoma. History. This section has been translated automatically. Shafer 1971. Definition. This section has been translated automatically. Probably traumatically induced, solitary, painless, xanthomatous neoplasm, which is preferably observed on the oral mucosa (especially hard palate or gingiva)
  3. Abstract. • We describe herein a patient with a verruciform xanthoma of the penis. This histologically distinctive lesion is usually confined to the oral mucosa, although two cases occurring on the vulva have recently been reported. To our knowledge, this lesion has not been previously described in other sites

CaseReport Oral Verruciform Xanthoma within Lichen Planus: A Case Report and Literature Review Vasileios I. Theofilou,1 Alexandra Sklavounou,1 Prokopios P. Argyris,2. Xanthoma Eruptive Xanthomas How To Diagnose Xanthoma What Causes tendon xanthomas verruciform xanthoma: This type of xanthoma is called verruciform because when examined under the microscope, it resembles another type of non-cancerous growth called verruca vulgaris. The lesions of this xanthoma large and flat and can involve the neck.

Webpathology

Verruciform xanthoma--biological profile of 282 oral

Verruciform xanthoma in an immunocompromised patient: a case report and immunohistochemical study. J Cutan Pathol. 1993 Feb. 20(1):84-6. . Blankenship DW, Zech L, Mirzabeigi M, Venna S. Verruciform xanthoma of the upper-extremity in the absence of chronic skin disease or syndrome: a case report and review of the literature. J Cutan. Whereas xanthoma are found surrounding the 'orbital septum', (very near the inside of the eyelid), xanthomas and xanthomatous can commonly also be found internally, in addition to on the surface in differing areas from the face. The yellowish papules seen in here are a form of planar xanthoma Applicable To. Broad- or floating-betalipoproteinemia; Combined hyperlipidemia NOS; Elevated cholesterol with elevated triglycerides NEC; Fredrickson's hyperlipoproteinemia, type IIb or II Interdigital xanthomas 出現在手指間的xanthoma,尤其是大拇指和食指,出現於同型合子的家族性高膽固醇血症. 病灶的切片有許多foam cell在真皮上層聚集. Normolipemic plane xanthoma 有些患者的plane xanthoma和高血脂無關 可能原因不明,或次發於血液科疾病(ex. MM) (5) Verruciform. Download Citation | On Feb 1, 2013, N. Shimamoto and others published Verruciform xanthoma | Find, read and cite all the research you need on ResearchGat

Verruciform xanthoma, a rare histopathologic entity first described by Shafer in 1971, consists of two major elements—a papillomatous proliferation of epithelial or epidermal cells and xanthomatous foam cell infiltrates present in the papillary dermis. Verruciform xanthoma is usually found on the oral mucosa, 1 but it also occurs, on rare instances, on the skin of the vulva, 2 groin, 3 and. Verruciform xanthoma (VX) is a relatively rare benign lesion and oral predominantly, which occasionally affects skin and genital mucosa. It appears as a papule or single plaque showing a verrucous or papillomatous aspect, with variable color from reddish pink to gray. In majority of oral cases, it affects gingiva and alveolar mucosa such Verruciform xanthoma is an uncommon oral soft tissue lesion orginally described by Shafer (1971). Twenty-six cases have been reported in the literature and the follow- ing three cases are believed to be the first recorded in the United Kingdom Verruciform Xanthoma. 川 内 康 弘 大 塚 藤 男 62歳男の陰嚢部に発生したVerruciform xanthomaの1例 を報告した。2年前から徐々 に大きさが増大し,初診時は有茎性,表 面細顆粒状,特有の赤橙色を呈する腫瘤であった Verruciform Xanthoma of a Lower Lip Lesion: A New Case and Review of the Literature. Download. Related Papers. Oral Verruciform Xanthoma Associated with Chronic Graft-Versus- Host Disease: A Report of Five Cases and a Review of the Literature. By ZAINAB KHAN and Shokoufeh Farahani

Path Exam 1 - Oral Maxillofacial Pathology µbiology 6252

Xanthoma DermNet N

verruciform xanthoma chronic hyperplastic candidiasis Actinic cheilitis Lupus erythematosus Lichen planus Dysplasia PVL SCC 0 8 15 23 30 1 1 20 11 2 9 2 1 7 2 1 22 1. ผลการดําเนินงาน SCC 1 PMD 46 Others 33 Lesion without pathological report 100 No lesion 862 Oral verruciform xanthoma represents an uncommon entity, which ae cts mainly oral mucosa. is paper presents the major clinical and histological features of oral verruciform xanthoma and reports a case on the tongue. e dierential diagnosis and

Verruciform xanthoma of the penis: A rare benign lesion

Verruciform xanthoma (VX) is an uncommon benign inflammatory mucocutaneous condition that chiefly occurs in the oral cavity. It is often associated with pre-existing epithelial and/or inflammatory disorder and is characterized histopathologically by papillary epithelial hyperplasia and the presence of foamy macrophages in connective tissue papillae Verruciform xanthoma is een zeldzame benigne afwijking van de mondholte. Het wordt ingedeeld onder de xanthomen, maar er is geen hyperlipidemie.Klinisch is het een gelige of oranjegele verruceuze papel of klein tumortje in de mondholte, vooral gingiva, palatum, soms tong Verruciform xanthoma is a rare lesion that occurs predominantly on the oral mucosae, but also on other mucosal sites and on the skin. We report an immunocytochemical analysis of the xanthoma cells in three cases of verruciform xanthoma (two vulval and one scrotal), and also attempt to identify human papilloma virus (HPV) as a possible trigger for the production of these lesions Oral verruciform xanthoma (OVX) is a rare benign lesion that was first reported in 1971 [1]. Microscopically, OVX is characterized by papillary or verrucous proliferation of squamous epithelium with keratosis and several foamy macrophages accumulated in the lamina propria papillae Verruciform xanthoma (VX) is an uncommon verrucous or flat small lesion usually located in gingiva. The etiology and pathogenesis of VX remain unknown, and many hypotheses have been suggested, including trauma, viruses, and immune response

Verruciform xanthoma: report of three patients with

Verruciform xanthoma [VX] is an uncommon benign mucocutaneous lesion of unknown etiology. This rare, harmless lesion usually presents as sessile or pedunculated, pale yellowish-to-red, papillary, granular or verrucous mucosal growth. Histologically VX is characterized by the presence of parakeratinzed epithelium showing papillary or verrucous growth with thin rete ridges and connective tissue. Verruciform xanthoma is a non-tumorous lesion of unknown etiology and uncertain nature, first described by Shafer in 1971.Histologically the characteristic features of the lesion are the presence of rete pegs extremely elongated and large, swollen foam cells or xanthoma cells.This paper presented the case of an 80-year-old female with a lesion at the right lateral margin of the tongue

Verruciform xanthoma is an uncommon, benign, asymptomatic lesion commonly affecting the attached tissues in the oral cavity, especially the gingiva. Clinical presentation can be variable and requires biopsy to confirm the diagnosis. Case Serie Background: Verruciform xanthoma is a benign verrucous lesion characterized by epithelial acanthosis and lipid-laden foamy histiocytes in the connective tissue papillae. It typically presents as a papillomatous, polypoid, or sessile lesion. Verruciform xanthoma is most commonly observed within the oral cavity Verruciform xanthoma is a rather rare lesion that is mostly confined to the oral mucosa. The clinical picture may vary considerably. The diagnosis is based on the presence of numerous xanthoma cells in the connective tissue papillae. A case of verruciform xanthoma on the gingiva in relation to lower right posterior region in a 43-year-old man.

Verruciform xanthoma - Dermatology Adviso

VERRUCIFORM XANTHOMA: The etiopathogenesis is obscure but may be related to trauma, chronic inflammation or solar injury. May also be associated with lichen planus, lichen sclerosus, pemphigus.. Verruciform xanthoma is a relatively uncommon lesion. Half of the reported cases occurred in the gingiva or alveolar ridge. In most cases, the clinical impressions are papilloma or verrucous carcinom.. Verruciform xanthoma is an uncommon benign lesion of undetermined aetiology. It is a superficial normo-lipemic xanthoma, probably reflecting a multifactorial reactive and dystrophic process. Its clinical and pathological recognition and correct diagnosis is critical because it can occur in conjunction with other systemic and cutaneous. The distribution of xanthomas in the mucous membranes of the dog in the current study mimics typical verruciform xanthoma in humans. Indeed, human verruciform xan-thoma is observed in many tissues and organs that are lined by stratified squamous epithelium, including the oral cavity (gingiva, soft and hard palate, tongue, lips, buccal mucosa. Verruciform xanthoma is an uncommon benign lesion that has a verruciform (wart-like) appearance, but it may appear polypoid, papillomatous, or sessile. The verruciform was first described by Shafer in 1971 on the oral mucosa. Usually found on the oral mucosa of middle-aged persons, verruciform xanthomas have also been reported on the scrotum.

Verruciform Xanthoma Differential Diagnose

Verruciform xanthoma is an uncommon benign lesion that has a verruciform (wart-like) appearance, but it may appear polypoid, papillomatous, or sessile. The verruciform was first described by Shafer in 1971 on the oral mucosa. Usually found on the oral mucosa of middle-aged persons, verruciform xanthomas have also been reported on the scrotum and penis of middle-aged to elderly Japanese males. verruciform xanthomaの意味や使い方 ゆうぜい型黄色腫; 疣贅型黄色腫 - 約1175万語ある英和辞典・和英辞典。発音・イディオムも分かる英語辞書 It is widely assumed that the Human papilloma Virus (HPV) is an etiologic factor of papillomas.1 The lesion may look wart-like or cauliflower like and may be difficult to differentiate clinically from verruca vul- garis, condyloma acuminatum, verruciform xanthoma or focal epithelial hyperplasia.2,

Oral Verruciform Xanthoma: A Case Report and Literature Revie

We describe five cases of verruciform xanthoma (VX). The patients, all males, presented with single warty verrucous lesions of 0.5-2 cm size that had been diagnosed clinically as viral warts (four cases) and leukoplakia (one case). Two patients had the lesion in the oral cavity, two on the genital mucosa, and one on the scrotal skin. Histopathology was diagnostic, with verrucous and.

Xanthogranuloma, juvenile; Nevoxanthoendothelioma